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Direct Synthesis of Chiral Porphyrin Macrocyclic Receptors via Regioselective Nitration

[Image: see text] Nitration of tetraphenylporphyrin cage compound 1, at −40 °C, leads to the regioselective formation of the chiral mononitro compound 2 (75% isolated yield) and, at −30 °C, to the achiral syn-dinitro-derivative 3 and the chiral anti-dinitro derivative 4 in a diastereomeric ratio of...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Varghese, Shaji, Spierenburg, Bram, Swartjes, Anne, White, Paul B., Tinnemans, Paul, Elemans, Johannes A. A. W., Nolte, Roeland J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038098/
https://ncbi.nlm.nih.gov/pubmed/29894198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b01055
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