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Repair of DNA double-strand breaks by mammalian alternative end-joining pathways

Alternative end-joining (a-EJ) pathways, which repair DNA double-strand breaks (DSBs), are initiated by end resection that generates 3′ single strands. This reaction is shared, at least in part, with homologous recombination but distinguishes a-EJ from the major nonhomologous end-joining pathway. Al...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Sallmyr, Annahita, Tomkinson, Alan E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036210/
https://ncbi.nlm.nih.gov/pubmed/29530982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM117.000375
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