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Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy
Therapeutic cancer vaccines require adjuvants leading to robust type I interferon and proinflammatory cytokine responses in the tumor microenvironment to induce an anti-tumor response. Cyclic dinucleotides (CDNs), a potent Stimulator of Interferon Receptor (STING) agonist, are currently in phase I t...
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| Publicado en: | Nanomedicine |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6035751/ https://ncbi.nlm.nih.gov/pubmed/29127039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2017.10.013 |
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