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Enhancing immunotherapy of STING agonist for lymphoma in preclinical models

Direct activation of tumor infiltrating antigen-presenting cells (APCs) by intratumoral injection of STING agonists (STINGa) leads to regression of the treated lymphoma tumor. Because STING activation induces apoptosis in lymphoma cells in vitro, we distinguished between the direct therapeutic vs th...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Sallets, Adrienne, Robinson, Sophie, Kardosh, Adel, Levy, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134215/
https://ncbi.nlm.nih.gov/pubmed/30194137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018020040
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