Enhancing immunotherapy of STING agonist for lymphoma in preclinical models

Direct activation of tumor infiltrating antigen-presenting cells (APCs) by intratumoral injection of STING agonists (STINGa) leads to regression of the treated lymphoma tumor. Because STING activation induces apoptosis in lymphoma cells in vitro, we distinguished between the direct therapeutic vs th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Adv
Prif Awduron: Sallets, Adrienne, Robinson, Sophie, Kardosh, Adel, Levy, Ronald
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2018
Pynciau:
Immunobiology and Immunotherapy
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134215/
https://ncbi.nlm.nih.gov/pubmed/30194137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018020040
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