Enhancing immunotherapy of STING agonist for lymphoma in preclinical models

Direct activation of tumor infiltrating antigen-presenting cells (APCs) by intratumoral injection of STING agonists (STINGa) leads to regression of the treated lymphoma tumor. Because STING activation induces apoptosis in lymphoma cells in vitro, we distinguished between the direct therapeutic vs th...

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Bibliografiska uppgifter
I publikationen:Blood Adv
Huvudupphovsmän: Sallets, Adrienne, Robinson, Sophie, Kardosh, Adel, Levy, Ronald
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2018
Ämnen:
Immunobiology and Immunotherapy
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134215/
https://ncbi.nlm.nih.gov/pubmed/30194137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018020040
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