IL-7 Receptor Heterogeneity as a Mechanism for Repertoire Change during Post-Depletional Homeostatic Proliferation and its Relation to Costimulation Blockade–Resistant Rejection

Kidney transplant patients treated with belatacept without depletional induction experience higher rates of acute rejection compared to patients treated with conventional immunosuppression. Costimulation blockade-resistant rejection (CoBRR) is associated with terminally differentiated T cells. Alemt...

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Bibliographic Details
Published in:Am J Transplant
Main Authors: Xu, He, Bendersky, Victoria A., Brennan, Todd V., Espinosa, Jaclyn R., Kirk, Allan D.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035390/
https://ncbi.nlm.nih.gov/pubmed/29136317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14589
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