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Paneth cell multi-potency induced by Notch activation following injury

Paneth cells are post-mitotic intestinal epithelial cells supporting the stem cell niche and mucosal immunity. Paneth cell pathologies are observed in various gastrointestinal diseases, however their plasticity and response to genomic and environmental challenges remains unclear. Using a knock-in al...

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Detalles Bibliográficos
Publicado en:Cell Stem Cell
Main Authors: Yu, Shiyan, Tong, Kevin, Zhao, Yanlin, Balasubramanian, Iyshwarya, Yap, George S., Ferraris, Ronaldo P., Bonder, Edward M., Verzi, Michael P., Gao, Nan
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035085/
https://ncbi.nlm.nih.gov/pubmed/29887318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.05.002
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