Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche

Communication between stem and niche supporting cells maintains the homeostasis of adult tissues. Wnt signaling is a crucial regulator of the stem cell niche, but the mechanism that governs Wnt ligand delivery in this compartment has not been fully investigated. We identified that Wnt secretion is p...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Das, Soumyashree, Yu, Shiyan, Sakamori, Ryotaro, Vedula, Pavan, Feng, Qiang, Flores, Juan, Hoffman, Andrew, Fu, Jiang, Stypulkowski, Ewa, Rodriguez, Alexis, Dobrowolski, Radek, Harada, Akihiro, Hsu, Wei, Bonder, Edward M., Verzi, Michael P., Gao, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483769/
https://ncbi.nlm.nih.gov/pubmed/26015543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.121046
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