Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche

Communication between stem and niche supporting cells maintains the homeostasis of adult tissues. Wnt signaling is a crucial regulator of the stem cell niche, but the mechanism that governs Wnt ligand delivery in this compartment has not been fully investigated. We identified that Wnt secretion is p...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Das, Soumyashree, Yu, Shiyan, Sakamori, Ryotaro, Vedula, Pavan, Feng, Qiang, Flores, Juan, Hoffman, Andrew, Fu, Jiang, Stypulkowski, Ewa, Rodriguez, Alexis, Dobrowolski, Radek, Harada, Akihiro, Hsu, Wei, Bonder, Edward M., Verzi, Michael P., Gao, Nan
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Stem Cells and Regeneration
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483769/
https://ncbi.nlm.nih.gov/pubmed/26015543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.121046
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