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Paneth cell multi-potency induced by Notch activation following injury

Paneth cells are post-mitotic intestinal epithelial cells supporting the stem cell niche and mucosal immunity. Paneth cell pathologies are observed in various gastrointestinal diseases, however their plasticity and response to genomic and environmental challenges remains unclear. Using a knock-in al...

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Dades bibliogràfiques
Publicat a:Cell Stem Cell
Autors principals: Yu, Shiyan, Tong, Kevin, Zhao, Yanlin, Balasubramanian, Iyshwarya, Yap, George S., Ferraris, Ronaldo P., Bonder, Edward M., Verzi, Michael P., Gao, Nan
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035085/
https://ncbi.nlm.nih.gov/pubmed/29887318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.05.002
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