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Role for IL-10 in the transcriptional regulation of Roquin-1
Roquin-1, a RING finger E3 ubiquitin ligase, functions as a modulator of inflammation; however, nothing is known about how Rc3h1 expression is regulated. Here, we describe an opposing relationship between Roquin-1 and the IL-17 proinflammatory cytokine by demonstrating that enforced expression of Rc...
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| Udgivet i: | Gene |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6034679/ https://ncbi.nlm.nih.gov/pubmed/25062971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2014.07.056 |
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