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Small Intestine Inflammation in Roquin-Mutant and Roquin-Deficient Mice
Roquin, an E3 ubiquitin ligase that localizes to cytosolic RNA granules, is involved in regulating mRNA stability and translation. Mice that have a M199R mutation in the Roquin protein (referred to as sanroque or Roquin(san/san) mice) develop autoimmune pathologies, although the extent to which thes...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581552/ https://ncbi.nlm.nih.gov/pubmed/23451046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056436 |
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