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Role for IL-10 in the transcriptional regulation of Roquin-1

Roquin-1, a RING finger E3 ubiquitin ligase, functions as a modulator of inflammation; however, nothing is known about how Rc3h1 expression is regulated. Here, we describe an opposing relationship between Roquin-1 and the IL-17 proinflammatory cytokine by demonstrating that enforced expression of Rc...

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Detalhes bibliográficos
Publicado no:Gene
Main Authors: Schaefer, Jeremy S., Montufar-Solis, Dina, Klein, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034679/
https://ncbi.nlm.nih.gov/pubmed/25062971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2014.07.056
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