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Inflammation leads through PGE/EP (3) signaling to HDAC5/MEF2‐dependent transcription in cardiac myocytes

The myocyte enhancer factor 2 (MEF2) regulates transcription in cardiac myocytes and adverse remodeling of adult hearts. Activators of G protein‐coupled receptors (GPCRs) have been reported to activate MEF2, but a comprehensive analysis of GPCR activators that regulate MEF2 has to our knowledge not...

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Bibliographic Details
Published in:EMBO Mol Med
Main Authors: Tóth, András D, Schell, Richard, Lévay, Magdolna, Vettel, Christiane, Theis, Philipp, Haslinger, Clemens, Alban, Felix, Werhahn, Stefanie, Frischbier, Lina, Krebs‐Haupenthal, Jutta, Thomas, Dominique, Gröne, Hermann‐Josef, Avkiran, Metin, Katus, Hugo A, Wieland, Thomas, Backs, Johannes
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034133/
https://ncbi.nlm.nih.gov/pubmed/29907596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708536
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