Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease

BACKGROUND & AIMS: The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and Crohn’s disease (CD) cause significant morbidity and are increasing in prevalence among all populations, including African Americans. More than 200 susceptibility loci have been identified in populations of pred...

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Publicat a:Gastroenterology
Autors principals: Brant, Steven R., Okou, David T., Simpson, Claire L., Cutler, David J., Haritunians, Talin, Bradfield, Jonathan P., Chopra, Pankaj, Prince, Jarod, Begum, Ferdouse, Kumar, Archana, Huang, Chengrui, Venkateswaran, Suresh, Datta, Lisa W., Wei, Zhi, Thomas, Kelly, Herrinton, Lisa J., Klapproth, Jan-Micheal A., Quiros, Antonio J., Seminerio, Jenifer, Liu, Zhenqiu, Alexander, Jonathan S., Baldassano, Robert N., Dudley-Brown, Sharon, Cross, Raymond K., Dassopoulos, Themistocles, Denson, Lee A., Dhere, Tanvi A., Dryden, Gerald W., Hanson, John S., Hou, Jason K., Hussain, Sunny Z., Hyams, Jeffrey S., Isaacs, Kim L., Kader, Howard, Kappelman, Michael D., Katz, Jeffry, Kellermayer, Richard, Kirschner, Barbara S., Kuemmerle, John F., Kwon, John H., Lazarev, Mark, Li, Ellen, Mack, David, Mannon, Peter, Moulton, Dedrick E., Newberry, Rodney D., Osuntokun, Bankole O., Patel, Ashish S., Saeed, Shehzad A., Targan, Stephan R., Valentine, John F., Wang, Ming-Hsi, Zonca, Martin, Rioux, John D., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H., Hakonarson, Hakon, Zwick, Michael E., McGovern, Dermot P. B., Kugathasan, Subra
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033331/
https://ncbi.nlm.nih.gov/pubmed/28478146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.02.041
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