Genome-wide Association Study Identifies African-Specific Susceptibility Loci in African Americans with Inflammatory Bowel Disease

BACKGROUND & AIMS: The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and Crohn’s disease (CD) cause significant morbidity and are increasing in prevalence among all populations, including African Americans. More than 200 susceptibility loci have been identified in populations of pred...

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Vydáno v:Gastroenterology
Hlavní autoři: Brant, Steven R., Okou, David T., Simpson, Claire L., Cutler, David J., Haritunians, Talin, Bradfield, Jonathan P., Chopra, Pankaj, Prince, Jarod, Begum, Ferdouse, Kumar, Archana, Huang, Chengrui, Venkateswaran, Suresh, Datta, Lisa W., Wei, Zhi, Thomas, Kelly, Herrinton, Lisa J., Klapproth, Jan-Micheal A., Quiros, Antonio J., Seminerio, Jenifer, Liu, Zhenqiu, Alexander, Jonathan S., Baldassano, Robert N., Dudley-Brown, Sharon, Cross, Raymond K., Dassopoulos, Themistocles, Denson, Lee A., Dhere, Tanvi A., Dryden, Gerald W., Hanson, John S., Hou, Jason K., Hussain, Sunny Z., Hyams, Jeffrey S., Isaacs, Kim L., Kader, Howard, Kappelman, Michael D., Katz, Jeffry, Kellermayer, Richard, Kirschner, Barbara S., Kuemmerle, John F., Kwon, John H., Lazarev, Mark, Li, Ellen, Mack, David, Mannon, Peter, Moulton, Dedrick E., Newberry, Rodney D., Osuntokun, Bankole O., Patel, Ashish S., Saeed, Shehzad A., Targan, Stephan R., Valentine, John F., Wang, Ming-Hsi, Zonca, Martin, Rioux, John D., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H., Hakonarson, Hakon, Zwick, Michael E., McGovern, Dermot P.B., Kugathasan, Subra
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5164948/
https://ncbi.nlm.nih.gov/pubmed/27693347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.09.032
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