Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease

BACKGROUND & AIMS: The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and Crohn’s disease (CD) cause significant morbidity and are increasing in prevalence among all populations, including African Americans. More than 200 susceptibility loci have been identified in populations of pred...

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Publicado no:Gastroenterology
Main Authors: Brant, Steven R., Okou, David T., Simpson, Claire L., Cutler, David J., Haritunians, Talin, Bradfield, Jonathan P., Chopra, Pankaj, Prince, Jarod, Begum, Ferdouse, Kumar, Archana, Huang, Chengrui, Venkateswaran, Suresh, Datta, Lisa W., Wei, Zhi, Thomas, Kelly, Herrinton, Lisa J., Klapproth, Jan-Micheal A., Quiros, Antonio J., Seminerio, Jenifer, Liu, Zhenqiu, Alexander, Jonathan S., Baldassano, Robert N., Dudley-Brown, Sharon, Cross, Raymond K., Dassopoulos, Themistocles, Denson, Lee A., Dhere, Tanvi A., Dryden, Gerald W., Hanson, John S., Hou, Jason K., Hussain, Sunny Z., Hyams, Jeffrey S., Isaacs, Kim L., Kader, Howard, Kappelman, Michael D., Katz, Jeffry, Kellermayer, Richard, Kirschner, Barbara S., Kuemmerle, John F., Kwon, John H., Lazarev, Mark, Li, Ellen, Mack, David, Mannon, Peter, Moulton, Dedrick E., Newberry, Rodney D., Osuntokun, Bankole O., Patel, Ashish S., Saeed, Shehzad A., Targan, Stephan R., Valentine, John F., Wang, Ming-Hsi, Zonca, Martin, Rioux, John D., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H., Hakonarson, Hakon, Zwick, Michael E., McGovern, Dermot P. B., Kugathasan, Subra
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033331/
https://ncbi.nlm.nih.gov/pubmed/28478146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.02.041
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