Lineage-specific functions of TET1 in the postimplantation mouse embryo

The mammalian TET enzymes catalyze DNA demethylation. While they have been intensely studied as major epigenetic regulators, little is known about their physiological roles and the extent of functional redundancy following embryo implantation. Here we define non-redundant roles for TET1 at an early...

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Publicat a:Nat Genet
Autors principals: Khoueiry, Rita, Sohni, Abhishek, Thienpont, Bernard, Luo, Xinlong, Velde, Joris Vande, Bartoccetti, Michela, Boeckx, Bram, Zwijsen, An, Rao, Anjana, Lambrechts, Diether, Koh, Kian Peng
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033328/
https://ncbi.nlm.nih.gov/pubmed/28504700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3868
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