Lineage-specific functions of TET1 in the postimplantation mouse embryo

The mammalian TET enzymes catalyze DNA demethylation. While they have been intensely studied as major epigenetic regulators, little is known about their physiological roles and the extent of functional redundancy following embryo implantation. Here we define non-redundant roles for TET1 at an early...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Khoueiry, Rita, Sohni, Abhishek, Thienpont, Bernard, Luo, Xinlong, Velde, Joris Vande, Bartoccetti, Michela, Boeckx, Bram, Zwijsen, An, Rao, Anjana, Lambrechts, Diether, Koh, Kian Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033328/
https://ncbi.nlm.nih.gov/pubmed/28504700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3868
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