Coordination of germ layer lineage choice by TET1 during primed pluripotency

Gastrulation in the early postimplantation stage mammalian embryo begins when epiblast cells ingress to form the primitive streak or develop as the embryonic ectoderm. The DNA dioxygenase Tet1 is highly expressed in the epiblast and yet continues to regulate lineage specification during gastrulation...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Luo, Xinlong, van der Veer, Bernard K., Sun, Lei, Bartoccetti, Michela, Boretto, Matteo, Vankelecom, Hugo, Khoueiry, Rita, Koh, Kian Peng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111260/
https://ncbi.nlm.nih.gov/pubmed/32115407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.329474.119
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