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Modeling Neurodegenerative Microenvironment Using Cortical Organoids Derived from Human Stem Cells

Alzheimer's disease (AD) is one of the most common neurodegenerative disorders and causes cognitive impairment and memory deficits of the patients. The mechanism of AD is not well known, due to lack of human brain models. Recently, mini-brain tissues called organoids have been derived from huma...

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Publicado en:Tissue Eng Part A
Autores principales: Yan, Yuanwei, Song, Liqing, Bejoy, Julie, Zhao, Jing, Kanekiyo, Takahisa, Bu, Guojun, Zhou, Yi, Li, Yan
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033307/
https://ncbi.nlm.nih.gov/pubmed/29361890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2017.0423
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