Genomics Analysis of Metabolic Pathways of Human Stem Cell-Derived Microglia-Like Cells and the Integrated Cortical Spheroids

Brain spheroids or organoids derived from human pluripotent stem cells (hiPSCs) are still not capable of completely recapitulating in vivo human brain tissue, and one of the limitations is lack of microglia. To add built-in immune function, coculture of the dorsal forebrain spheroids with isogenic m...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Bejoy, Julie, Yuan, Xuegang, Song, Liqing, Hua, Thien, Jeske, Richard, Sart, Sébastien, Sang, Qing-Xiang Amy, Li, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885849/
https://ncbi.nlm.nih.gov/pubmed/31827525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2382534
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