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Assembly of Human Stem Cell-Derived Cortical Spheroids and Vascular Spheroids to Model 3-D Brain-like Tissues

Human cerebral organoids derived from induced pluripotent stem cells (iPSCs) provide novel tools for recapitulating the cytoarchitecture of human brain and for studying biological mechanisms of neurological disorders. However, the heterotypic interactions of neurovascular units, composed of neurons,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Song, Liqing, Yuan, Xuegang, Jones, Zachary, Griffin, Kyle, Zhou, Yi, Ma, Teng, Li, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461701/
https://ncbi.nlm.nih.gov/pubmed/30979929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42439-9
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