Genomics Analysis of Metabolic Pathways of Human Stem Cell-Derived Microglia-Like Cells and the Integrated Cortical Spheroids

Brain spheroids or organoids derived from human pluripotent stem cells (hiPSCs) are still not capable of completely recapitulating in vivo human brain tissue, and one of the limitations is lack of microglia. To add built-in immune function, coculture of the dorsal forebrain spheroids with isogenic m...

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Vydáno v:Stem Cells Int
Hlavní autoři: Bejoy, Julie, Yuan, Xuegang, Song, Liqing, Hua, Thien, Jeske, Richard, Sart, Sébastien, Sang, Qing-Xiang Amy, Li, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885849/
https://ncbi.nlm.nih.gov/pubmed/31827525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2382534
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