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Modeling Neurodegenerative Microenvironment Using Cortical Organoids Derived from Human Stem Cells

Alzheimer's disease (AD) is one of the most common neurodegenerative disorders and causes cognitive impairment and memory deficits of the patients. The mechanism of AD is not well known, due to lack of human brain models. Recently, mini-brain tissues called organoids have been derived from huma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Tissue Eng Part A
Hauptverfasser: Yan, Yuanwei, Song, Liqing, Bejoy, Julie, Zhao, Jing, Kanekiyo, Takahisa, Bu, Guojun, Zhou, Yi, Li, Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033307/
https://ncbi.nlm.nih.gov/pubmed/29361890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2017.0423
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