Everolimus dosing recommendations for tuberous sclerosis complex–associated refractory seizures

OBJECTIVE: The present analysis examined the exposure‐response relationship by means of the predose everolimus concentration (C (min)) and the seizure response in patients with tuberous sclerosis complex–associated seizures in the EXIST‐3 study. Recommendations have been made for the target C (min)...

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Veröffentlicht in:Epilepsia
Hauptverfasser: Franz, David N., Lawson, John A., Yapici, Zuhal, Brandt, Christian, Kohrman, Michael H., Wong, Michael, Milh, Mathieu, Wiemer‐Kruel, Adelheid, Voi, Maurizio, Coello, Neva, Cheung, Wing, Grosch, Kai, French, Jacqueline A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
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Full‐length Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033043/
https://ncbi.nlm.nih.gov/pubmed/29727013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.14085
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