Everolimus dosing recommendations for tuberous sclerosis complex–associated refractory seizures

OBJECTIVE: The present analysis examined the exposure‐response relationship by means of the predose everolimus concentration (C (min)) and the seizure response in patients with tuberous sclerosis complex–associated seizures in the EXIST‐3 study. Recommendations have been made for the target C (min)...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Franz, David N., Lawson, John A., Yapici, Zuhal, Brandt, Christian, Kohrman, Michael H., Wong, Michael, Milh, Mathieu, Wiemer‐Kruel, Adelheid, Voi, Maurizio, Coello, Neva, Cheung, Wing, Grosch, Kai, French, Jacqueline A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Full‐length Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033043/
https://ncbi.nlm.nih.gov/pubmed/29727013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.14085
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