Everolimus dosing recommendations for tuberous sclerosis complex–associated refractory seizures

OBJECTIVE: The present analysis examined the exposure‐response relationship by means of the predose everolimus concentration (C (min)) and the seizure response in patients with tuberous sclerosis complex–associated seizures in the EXIST‐3 study. Recommendations have been made for the target C (min)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Epilepsia
Prif Awduron: Franz, David N., Lawson, John A., Yapici, Zuhal, Brandt, Christian, Kohrman, Michael H., Wong, Michael, Milh, Mathieu, Wiemer‐Kruel, Adelheid, Voi, Maurizio, Coello, Neva, Cheung, Wing, Grosch, Kai, French, Jacqueline A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Full‐length Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033043/
https://ncbi.nlm.nih.gov/pubmed/29727013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.14085
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