Exploring the role of post‐translational modifications in regulating α‐synuclein interactions by studying the effects of phosphorylation on nanobody binding

Intracellular deposits of α‐synuclein in the form of Lewy bodies are major hallmarks of Parkinson's disease (PD) and a range of related neurodegenerative disorders. Post‐translational modifications (PTMs) of α‐synuclein are increasingly thought to be major modulators of its structure, function,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Protein Sci
Päätekijät: El Turk, Farah, De Genst, Erwin, Guilliams, Tim, Fauvet, Bruno, Hejjaoui, Mirva, Di Trani, Justin, Chiki, Anass, Mittermaier, Anthony, Vendruscolo, Michele, Lashuel, Hilal A., Dobson, Christopher M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Full‐Length Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032363/
https://ncbi.nlm.nih.gov/pubmed/29603451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3412
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