Exploring the role of post‐translational modifications in regulating α‐synuclein interactions by studying the effects of phosphorylation on nanobody binding

Intracellular deposits of α‐synuclein in the form of Lewy bodies are major hallmarks of Parkinson's disease (PD) and a range of related neurodegenerative disorders. Post‐translational modifications (PTMs) of α‐synuclein are increasingly thought to be major modulators of its structure, function,...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Protein Sci
Κύριοι συγγραφείς: El Turk, Farah, De Genst, Erwin, Guilliams, Tim, Fauvet, Bruno, Hejjaoui, Mirva, Di Trani, Justin, Chiki, Anass, Mittermaier, Anthony, Vendruscolo, Michele, Lashuel, Hilal A., Dobson, Christopher M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley and Sons Inc. 2018
Θέματα:
Full‐Length Papers
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032363/
https://ncbi.nlm.nih.gov/pubmed/29603451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3412
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