Exploring the role of post‐translational modifications in regulating α‐synuclein interactions by studying the effects of phosphorylation on nanobody binding

Intracellular deposits of α‐synuclein in the form of Lewy bodies are major hallmarks of Parkinson's disease (PD) and a range of related neurodegenerative disorders. Post‐translational modifications (PTMs) of α‐synuclein are increasingly thought to be major modulators of its structure, function,...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: El Turk, Farah, De Genst, Erwin, Guilliams, Tim, Fauvet, Bruno, Hejjaoui, Mirva, Di Trani, Justin, Chiki, Anass, Mittermaier, Anthony, Vendruscolo, Michele, Lashuel, Hilal A., Dobson, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Full‐Length Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032363/
https://ncbi.nlm.nih.gov/pubmed/29603451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3412
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