Alpha-synuclein Post-translational Modifications as Potential Biomarkers for Parkinson Disease and Other Synucleinopathies

The development of novel therapies against neurodegenerative disorders requires the ability to detect their early, presymptomatic manifestations in order to enable treatment before irreversible cellular damage occurs. Precocious signs indicative of neurodegeneration include characteristic changes in...

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Bibliographic Details
Main Authors: Schmid, Adrien W., Fauvet, Bruno, Moniatte, Marc, Lashuel, Hilal A.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2013
Subjects:
Special Issue: Post-translational Modifications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861707/
https://ncbi.nlm.nih.gov/pubmed/23966418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.R113.032730
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