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Depletion of amyloid‐β peptides from solution by sequestration within fibril‐seeded hydrogels

Aggregation of amyloid‐β (Aβ) peptides in brain tissue leads to neurodegeneration in Alzheimer's disease (AD). Regardless of the kinetics or detailed mechanisms of Aβ aggregation, aggregation can only occur if Aβ concentrations exceed their local equilibrium solubility values. We propose that e...

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Detaylı Bibliyografya
Yayımlandı:Protein Sci
Asıl Yazarlar: Yau, Wai‐Ming, Tycko, Robert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032349/
https://ncbi.nlm.nih.gov/pubmed/29417648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3387
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