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Rho GTPases in Intellectual Disability: From Genetics to Therapeutic Opportunities

Rho-class small GTPases are implicated in basic cellular processes at nearly all brain developmental steps, from neurogenesis and migration to axon guidance and synaptic plasticity. GTPases are key signal transducing enzymes that link extracellular cues to the neuronal responses required for the con...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zamboni, Valentina, Jones, Rebecca, Umbach, Alessandro, Ammoni, Alessandra, Passafaro, Maria, Hirsch, Emilio, Merlo, Giorgio R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032284/
https://ncbi.nlm.nih.gov/pubmed/29925821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061821
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