Structure–Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells

Schistosomiasis, caused by helminth flatworms of the genus Schistosoma, is an infectious disease mainly associated with poverty that affects millions of people worldwide. Since treatment for this disease relies only on the use of praziquantel, there is an urgent need to identify new antischistosomal...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Campelo, Yuri, Ombredane, Alicia, Vasconcelos, Andreanne G., Albuquerque, Lucas, Moreira, Daniel C., Plácido, Alexandra, Rocha, Jefferson, Hilarion Fokoue, Harold, Yamaguchi, Lydia, Mafud, Ana, Mascarenhas, Yvonne P., Delerue-Matos, Cristina, Borges, Tatiana, Joanitti, Graziella A., Arcanjo, D. R. Daniel, Kato, Massuo J., Kuckelhaus, Selma A. S., Silva, Marcos P. N., de Moraes, Josué, Leite, José Roberto S. A.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032158/
https://ncbi.nlm.nih.gov/pubmed/29921756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061802
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