Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity

Schistosomiasis is a disease caused by parasites of the genus Schistosoma, currently affecting more than 200 million people. Among the various species of this parasite that infect humans, S. mansoni is the most common. Pharmacological treatment is limited to the use of a single drug, praziquantel (P...

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Udgivet i:PLoS One
Main Authors: Guimarães, Maria A., de Oliveira, Rosimeire N., de Almeida, Rebeca L., Mafud, Ana C., Sarkis, Ana L. V., Ganassin, Rayane, da Silva, Marcos P., Roquini, Daniel B., Veras, Leiz M., Sawada, Tânia C. H., Ropke, Cristina D., Muehlmann, Luis A., Joanitti, Graziella A., Kuckelhaus, Selma A. S., Allegretti, Silmara M., Mascarenhas, Yvonne P., de Moraes, Josué, Leite, José R. S. A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947907/
https://ncbi.nlm.nih.gov/pubmed/29750792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196667
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