Structure–Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells

Schistosomiasis, caused by helminth flatworms of the genus Schistosoma, is an infectious disease mainly associated with poverty that affects millions of people worldwide. Since treatment for this disease relies only on the use of praziquantel, there is an urgent need to identify new antischistosomal...

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Publicado no:Int J Mol Sci
Main Authors: Campelo, Yuri, Ombredane, Alicia, Vasconcelos, Andreanne G., Albuquerque, Lucas, Moreira, Daniel C., Plácido, Alexandra, Rocha, Jefferson, Hilarion Fokoue, Harold, Yamaguchi, Lydia, Mafud, Ana, Mascarenhas, Yvonne P., Delerue-Matos, Cristina, Borges, Tatiana, Joanitti, Graziella A., Arcanjo, D. R. Daniel, Kato, Massuo J., Kuckelhaus, Selma A. S., Silva, Marcos P. N., de Moraes, Josué, Leite, José Roberto S. A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032158/
https://ncbi.nlm.nih.gov/pubmed/29921756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061802
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