Structure–Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells

Schistosomiasis, caused by helminth flatworms of the genus Schistosoma, is an infectious disease mainly associated with poverty that affects millions of people worldwide. Since treatment for this disease relies only on the use of praziquantel, there is an urgent need to identify new antischistosomal...

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Publié dans:Int J Mol Sci
Auteurs principaux: Campelo, Yuri, Ombredane, Alicia, Vasconcelos, Andreanne G., Albuquerque, Lucas, Moreira, Daniel C., Plácido, Alexandra, Rocha, Jefferson, Hilarion Fokoue, Harold, Yamaguchi, Lydia, Mafud, Ana, Mascarenhas, Yvonne P., Delerue-Matos, Cristina, Borges, Tatiana, Joanitti, Graziella A., Arcanjo, D. R. Daniel, Kato, Massuo J., Kuckelhaus, Selma A. S., Silva, Marcos P. N., de Moraes, Josué, Leite, José Roberto S. A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032158/
https://ncbi.nlm.nih.gov/pubmed/29921756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061802
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