TGF-β1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a c-Jun NH(2)-terminal kinase-1-dependent manner

Epithelial cells have been suggested as potential drivers of lung fibrosis, although the epithelial-dependent pathways that promote fibrogenesis remain unknown. Extracellular matrix is increasingly recognized as an environment that can drive cellular responses in various pulmonary diseases. In this...

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Publicado en:Am J Physiol Lung Cell Mol Physiol
Autores principales: van der Velden, Jos L., Wagner, Darcy E., Lahue, Karolyn G., Abdalla, Sarah T., Lam, Ying-Wai, Weiss, Daniel J., Janssen-Heininger, Yvonne M. W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032072/
https://ncbi.nlm.nih.gov/pubmed/29469614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00053.2017
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