Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers

To optimally penetrate biological hydrogels such as mucus and the tumor interstitial matrix, nanoparticles (NPs) require physicochemical properties that would typically preclude cellular uptake, resulting in inefficient drug delivery. Here, we demonstrate that (poly(lactic-co-glycolic acid) (PLGA) c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yu, Miaorong, Xu, Lu, Tian, Falin, Su, Qian, Zheng, Nan, Yang, Yiwei, Wang, Jiuling, Wang, Aohua, Zhu, Chunliu, Guo, Shiyan, Zhang, XinXin, Gan, Yong, Shi, Xinghua, Gao, Huajian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031689/
https://ncbi.nlm.nih.gov/pubmed/29973592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05061-3
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