Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers

To optimally penetrate biological hydrogels such as mucus and the tumor interstitial matrix, nanoparticles (NPs) require physicochemical properties that would typically preclude cellular uptake, resulting in inefficient drug delivery. Here, we demonstrate that (poly(lactic-co-glycolic acid) (PLGA) c...

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Bibliographic Details
Published in:	Nat Commun
Main Authors:	Yu, Miaorong, Xu, Lu, Tian, Falin, Su, Qian, Zheng, Nan, Yang, Yiwei, Wang, Jiuling, Wang, Aohua, Zhu, Chunliu, Guo, Shiyan, Zhang, XinXin, Gan, Yong, Shi, Xinghua, Gao, Huajian
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group UK 2018
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6031689/ https://ncbi.nlm.nih.gov/pubmed/29973592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05061-3
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Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers

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