Rapid transport of germ-mimetic nanoparticles with dual conformational polyethylene glycol chains in biological tissues

Polyethylene glycols (PEGs) can improve the diffusivity of nanoparticles (NPs) in biological hydrogels, while extended PEG chains severely impede cellular uptake of NPs. Inspired by invasive germs with flagellum-driven mucus-penetrating and fimbriae-mediated epithelium-adhering abilities, we develop...

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Udgivet i:Sci Adv
Main Authors: Yang, Yiwei, Tian, Falin, Nie, Di, Liu, Yuan, Qian, Kun, Yu, Miaorong, Wang, Aohua, Zhang, Yaqi, Shi, Xinghua, Gan, Yong
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007268/
https://ncbi.nlm.nih.gov/pubmed/32083187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9937
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