Rapid transport of germ-mimetic nanoparticles with dual conformational polyethylene glycol chains in biological tissues

Polyethylene glycols (PEGs) can improve the diffusivity of nanoparticles (NPs) in biological hydrogels, while extended PEG chains severely impede cellular uptake of NPs. Inspired by invasive germs with flagellum-driven mucus-penetrating and fimbriae-mediated epithelium-adhering abilities, we develop...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Yang, Yiwei, Tian, Falin, Nie, Di, Liu, Yuan, Qian, Kun, Yu, Miaorong, Wang, Aohua, Zhang, Yaqi, Shi, Xinghua, Gan, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007268/
https://ncbi.nlm.nih.gov/pubmed/32083187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9937
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