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Differential Neurotoxicity Related to Tetracycline Transactivator and TDP-43 Expression in Conditional TDP-43 Mouse Model of Frontotemporal Lobar Degeneration

Frontotemporal lobar degeneration (FTLD) is among the most prevalent dementias of early-onset. Pathologically, FTLD presents with tauopathy or TAR DNA-binding protein 43 (TDP-43) proteinopathy. A biallelic mouse model of FTLD was produced on a mix FVB/129SVE background overexpressing wild-type human...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Kukreja, L., Shahidehpour, R., Kim, G., Keegan, J., Sadleir, K.R., Russell, T., Csernansky, J., Mesulam, M., Vassar, R.J., Wang, L., Dong, H., Geula, C.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031584/
https://ncbi.nlm.nih.gov/pubmed/29807909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1836-17.2018
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