Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo

Lineage segregation in the mouse embryo is a finely controlled process dependent upon coordination of signalling pathways and transcriptional responses. Here we employ a conditional deletion system to investigate embryonic patterning and lineage specification in response to loss of Oct4. We first ob...

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Dades bibliogràfiques
Publicat a:Development
Autors principals: Mulas, Carla, Chia, Gloryn, Jones, Kenneth Alan, Hodgson, Andrew Christopher, Stirparo, Giuliano Giuseppe, Nichols, Jennifer
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2018
Matèries:
Stem Cells and Regeneration
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031404/
https://ncbi.nlm.nih.gov/pubmed/29915126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.159103
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