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Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo
Lineage segregation in the mouse embryo is a finely controlled process dependent upon coordination of signalling pathways and transcriptional responses. Here we employ a conditional deletion system to investigate embryonic patterning and lineage specification in response to loss of Oct4. We first ob...
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| Publicado no: | Development |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6031404/ https://ncbi.nlm.nih.gov/pubmed/29915126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.159103 |
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