CDK6 antagonizes p53-induced responses during tumorigenesis

Tumor formation is a multi-step process during which cells acquire genetic and epigenetic changes until they reach a fully transformed state. We show that CDK6 contributes to tumor formation by regulating transcriptional responses in a stage-specific manner. In early stages CDK6 kinase induces a com...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Cancer Discov
Main Authors: Bellutti, Florian, Tigan, Anca-Sarmiza, Nebenfuehr, Sofie, Dolezal, Marlies, Zojer, Markus, Grausenburger, Reinhard, Hartenberger, Svenja, Kollmann, Sebastian, Doma, Eszter, Prchal-Murphy, Michaela, Uras, Iris Z., Höllein, Alexander, Neuberg, Donna S., Ebert, Benjamin L., Ringler, Anna, Mueller, Andre C., Loizou, Joanna I., Hinds, Philip W., Vogl, Claus, Heller, Gerwin, Kubicek, Stefan, Zuber, Johannes, Malumbres, Marcos, Farlik, Matthias, Villunger, Andreas, Kollmann, Karoline, Sexl, Veronika
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031305/
https://ncbi.nlm.nih.gov/pubmed/29899063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0912
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla