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The Effect of CDK6 Expression on DNA Methylation and DNMT3B Regulation

CDK6 is frequently overexpressed in various cancer types and functions as a positive regulator of the cell cycle and as a coregulator of gene transcription. We provide evidence that CDK6 is involved in the process of DNA methylation, at least in ALL. We observe a positive correlation of CDK6 and DNM...

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Библиографические подробности
Опубликовано в: :iScience
Главные авторы: Heller, Gerwin, Nebenfuehr, Sofie, Bellutti, Florian, Ünal, Huriye, Zojer, Markus, Scheiblecker, Lisa, Sexl, Veronika, Kollmann, Karoline
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648139/
https://ncbi.nlm.nih.gov/pubmed/33205015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101602
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