CDK6 antagonizes p53-induced responses during tumorigenesis

Tumor formation is a multi-step process during which cells acquire genetic and epigenetic changes until they reach a fully transformed state. We show that CDK6 contributes to tumor formation by regulating transcriptional responses in a stage-specific manner. In early stages CDK6 kinase induces a com...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cancer Discov
Κύριοι συγγραφείς: Bellutti, Florian, Tigan, Anca-Sarmiza, Nebenfuehr, Sofie, Dolezal, Marlies, Zojer, Markus, Grausenburger, Reinhard, Hartenberger, Svenja, Kollmann, Sebastian, Doma, Eszter, Prchal-Murphy, Michaela, Uras, Iris Z., Höllein, Alexander, Neuberg, Donna S., Ebert, Benjamin L., Ringler, Anna, Mueller, Andre C., Loizou, Joanna I., Hinds, Philip W., Vogl, Claus, Heller, Gerwin, Kubicek, Stefan, Zuber, Johannes, Malumbres, Marcos, Farlik, Matthias, Villunger, Andreas, Kollmann, Karoline, Sexl, Veronika
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2018
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031305/
https://ncbi.nlm.nih.gov/pubmed/29899063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0912
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