AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation

The ubiquitin-directed AAA-ATPase VCP/p97 facilitates degradation of damaged or misfolded proteins in diverse cellular stress response pathways. Resolving the complexity of its interactions with partner and substrate proteins and understanding its links to stress signaling is therefore a major chall...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Proteomics
Prif Awduron: Hülsmann, Julia, Kravic, Bojana, Weith, Matthias, Gstaiger, Matthias, Aebersold, Ruedi, Collins, Ben C., Meyer, Hemmo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030730/
https://ncbi.nlm.nih.gov/pubmed/29599191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000471
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