AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation

The ubiquitin-directed AAA-ATPase VCP/p97 facilitates degradation of damaged or misfolded proteins in diverse cellular stress response pathways. Resolving the complexity of its interactions with partner and substrate proteins and understanding its links to stress signaling is therefore a major chall...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Hülsmann, Julia, Kravic, Bojana, Weith, Matthias, Gstaiger, Matthias, Aebersold, Ruedi, Collins, Ben C., Meyer, Hemmo
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030730/
https://ncbi.nlm.nih.gov/pubmed/29599191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000471
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