AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation

The ubiquitin-directed AAA-ATPase VCP/p97 facilitates degradation of damaged or misfolded proteins in diverse cellular stress response pathways. Resolving the complexity of its interactions with partner and substrate proteins and understanding its links to stress signaling is therefore a major chall...

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Detalles Bibliográficos
Publicado en:Mol Cell Proteomics
Main Authors: Hülsmann, Julia, Kravic, Bojana, Weith, Matthias, Gstaiger, Matthias, Aebersold, Ruedi, Collins, Ben C., Meyer, Hemmo
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030730/
https://ncbi.nlm.nih.gov/pubmed/29599191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000471
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