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The VCP/p97 system at a glance: connecting cellular function to disease pathogenesis
The ATPase valosin-containing protein (VCP)/p97 has emerged as a central and important element of the ubiquitin system. Together with a network of cofactors, it regulates an ever-expanding range of processes that stretch into almost every aspect of cellular physiology. Its main role in proteostasis...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4163641/ https://ncbi.nlm.nih.gov/pubmed/25146396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.093831 |
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