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The VCP/p97 system at a glance: connecting cellular function to disease pathogenesis

The ATPase valosin-containing protein (VCP)/p97 has emerged as a central and important element of the ubiquitin system. Together with a network of cofactors, it regulates an ever-expanding range of processes that stretch into almost every aspect of cellular physiology. Its main role in proteostasis...

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Détails bibliographiques
Auteurs principaux: Meyer, Hemmo, Weihl, Conrad C.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163641/
https://ncbi.nlm.nih.gov/pubmed/25146396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.093831
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