Nanobody-antigen conjugates elicit HPV-specific antitumor immune responses

High-risk human papillomavirus-associated cancers express viral oncoproteins (e.g., E6 and E7) that induce and maintain the malignant phenotype. The viral origin of these proteins makes them attractive targets for development of a therapeutic vaccine. Camelid-derived single-domain antibody fragments...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Woodham, Andrew W, Cheloha, Ross W, Ling, Jingjing, Rashidian, Mohammad, Kolifrath, Stephen C, Mesyngier, Maia, Duarte, Joao N, Bader, Justin M, Skeate, Joseph G, Da Silva, Diane M, Kast, W Martin, Ploegh, Hidde L
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030498/
https://ncbi.nlm.nih.gov/pubmed/29792298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0661
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